Back
RESEARCH PLATFORM 1

R.P 1.3 Advanced Technologies for Prediction of Myopia Progression

DOWNLOAD POSTER
Advanced Technologies for Prediction of Myopia Progression

Principle Investigators

PolyU
Prof. Ho-lung Henry CHAN

Prof. Ho-lung Henry CHAN
Prof. Chea-su KEE

Prof. Chea-su KEE
UWaterloo
Prof. Daphne MCCULLOCH

Prof. Daphne MCCULLOCH
Prof. Ben THOMPSON

Prof. Ben THOMPSON
Co-I
Dr. Kai-yip CHOI

Dr. Kai-yip CHOI
Dr. Elie de LESTRANGE-ANGINIEUR

Dr. Elie de LESTRANGE-ANGINIEUR
Prof. Mingguang HE

Prof. Mingguang HE
Dr. Byung-soo Jeremy KANG

Dr. Byung-soo Jeremy KANG
Prof. Tsz-wing Jeffrey LEUNG

Prof. Tsz-wing Jeffrey LEUNG
Dr. Vivian CHOH

Dr. Vivian CHOH
Prof. Elizabeth IRVING

Prof. Elizabeth IRVING
Prof. Vivek MAHESHWARI

Prof. Vivek MAHESHWARI
Dr. Stanley WOO

Dr. Stanley WOO

Aims

To develop a data analytics platform that can predict myopia progression and recommend early, personalized treatment based on novel measurements of eye structure and function. The project will advance two technology areas: 1) clinical testing and deployment of a platform that uses well established measurements of ocular biometry in a novel predictive algorithm to provide personalized myopia treatment recommendations; 2) the development of novel structural and functional measures of the eye that will enable more precise prediction of myopia progression.

 

Background

Myopia is a significant vision health issue, with an estimated 50% of the global population expected to be affected by 2025. About 20% of those with myopia will develop high myopia. By 2050, high myopia is projected to affect 1 billion people, placing major stress on economies and healthcare systems. Early and accurate prediction of high myopia progression could enable targeted treatments to preserve sight.

 

Work to be Done

The first phase focuses on the development and clinical validation of a Digital Myopia Control (d.MC™) platform that incorporates patented predictive algorithms based on ocular biometrics for monitoring eye growth, offering a novel approach to managing myopia. The d.MC™ platform aims to provide personalized treatment plans to slow down the progression of myopia, thereby reducing the risk of severe ocular complications. In parallel to the predictive algorithm, a novel dual technology of using both OCT+ERG will be developed to monitor progressive changes in retinal cellular structure, function, and vasculature during different stages of myopia development. The combination of OCT+ERG technologies into a single tool can provide eye care practitioners with a comprehensive approach to examining the progression of myopia and the effectiveness of novel treatment approaches.

 

Benefits

The potential beneficiaries encompass all children at risk of developing myopia. The prediction of myopia progression through OCT+ERG measurement represents the sole current objective method for assessing retinal activity associated with myopia progression. The combination of OCT+ERG technologies can provide a more comprehensive approach to examining the progression of juvenile myopia and the effectiveness of novel treatment approaches.

 

Impact

Identify individuals at risk of high myopia-related retinal degeneration, allowing appropriate early intervention to halt or slow myopia progression. This approach will allow comprehensive myopia management to offer a personalized approach to treatment. Consequently, to prevent the onset of severe ocular complications, such as retinal detachment, macular degeneration, cataracts, and glaucoma, preserving the vision of individuals with myopia and enhancing their quality of life.

 

 

Learn more about R.P 1.2 Learn more about R.P 1.4

Learn More About Other Research Projects

R.P 1.1 Development and Clinical Validation of AI-Based Software as a Medical Device for Non-Invasive Ophthalmic Imaging and Automated Reporting

Development and Clinical Validation of AI-Based Software as a Medical Device for Non-Invasive Ophthalmic Imaging and Automated Reporting

R.P 1.2 Anti-Myopia Electronic Displays: Making Screens Eye-Safe for Children

Anti-Myopia Electronic Displays: Making Screens Eye-Safe for Children

R.P 1.4 Targeting Higher-Level Brain Functions for Amblyopia Rehabilitation

Targeting Higher-Level Brain Functions for Amblyopia Rehabilitation

R.P 1.5 Novel Neuromodulation Approaches for Vision Enhancement in Adults

Novel Neuromodulation Approaches for Vision Enhancement in Adults

R.P 2.1 Clinical Translation of a Novel Anti-Microbial Therapy for Eye Infections

Clinical Translation of a Novel Anti-Microbial Therapy for Eye Infections

R.P 2.2 An Organoid Platform and Cell-Based Platform for Ocular Therapeutic Development

An Organoid Platform and Cell-Based Platform for Ocular Therapeutic Development

R.P 2.3 Developing Next-Generation Therapeutic Agents for Glaucoma

Developing Next-Generation Therapeutic Agents for Glaucoma

R.P 2.4 Novel Gene Delivery Platforms for the Treatment of Ocular Disease

Novel Gene Delivery Platforms for the Treatment of Ocular Disease

R.P 2.5 Integrated Dry Eye Diagnosis and Precision Therapies

Integrated Dry Eye Diagnosis and Precision Therapies

R.P 2.6 Development of Ocular Inserts and Aptamer-Based Delivery Vehicles for Sustained Release of Ocular Therapeutics and TCM Products

Development of Ocular Inserts and Aptamer-Based Delivery Vehicles for Sustained Release of Ocular Therapeutics and TCM Products

R.P 3.1 Eye Disease Diagnosis and Treatment Enabled by Novel Retinal Instrumentation

Eye Disease Diagnosis and Treatment Enabled by Novel Retinal Instrumentation

R.P 3.2 Non-Invasive Tear-Based Diagnostic System

Non-Invasive Tear-Based Diagnostic System

R.P 3.3 Development of New-Generation Contact Lenses Using Novel Materials and Additive Manufacturing

Development of New-Generation Contact Lenses Using Novel Materials and Additive Manufacturing

R.P 3.4 Detection of Macular Degeneration and Myopia-Induced Retinal Damage Using Structured Light Technology

Detection of Macular Degeneration and Myopia-Induced Retinal Damage Using Structured Light Technology

R.P 3.5 Extended Reality Visual Intelligence System (XRVIS) for Tele-Visual Assessment and Safety Enhancement for People with Visual Impairment

Extended Reality Visual Intelligence System (XRVIS) for Tele-Visual Assessment and Safety Enhancement for People with Visual Impairment