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RESEARCH PLATFORM 1

R.P 1.4 Targeting Higher-Level Brain Functions for Amblyopia Rehabilitation

Principle Investigators

PolyU

Prof. Ming-yan Allen CHEONG

Prof. Tsz-wing Jeffrey LEUNG

UWaterloo

Dr. Krista KELLY

Prof. Benjamin THOMPSON

Overview

Amblyopia is a neurodevelopmental disorder characterized by reduced visual acuity in one or both eyes, significantly impairing visual acuity and 3D vision (stereopsis). This project aims to develop a novel rehabilitation approach for amblyopia in both children and adults by targeting higher-level brain mechanisms related to visual attention. Building on evidence that neuroplasticity persists in the adult brain, the study focuses on improving binocular and 3D vision rather than visual acuity alone. The work involves creating a new visual-attention–based training framework, including a web-based, home-use program delivered through personal devices, complemented by clinic-based and home-based neuromodulation technologies designed to enhance neuroplasticity and accelerate visual recovery.

Learn more about R.P 1.3 Learn more about R.P 1.5

R.P 1.1 Development and Clinical Validation of AI-Based Software as a Medical Device for Non-Invasive Ophthalmic Imaging and Automated Reporting

Development and Clinical Validation of AI-Based Software as a Medical Device for Non-Invasive Ophthalmic Imaging and Automated Reporting

R.P 1.2 Anti-Myopia Electronic Displays: Making Screens Eye-Safe for Children

R.P 1.3 Advanced Technologies for Prediction of Myopia Progression

R.P 1.5 Novel Neuromodulation Approaches for Vision Enhancement in Adults

R.P 2.1 Clinical Translation of a Novel Anti-Microbial Therapy for Eye Infections

R.P 2.2 An Organoid Platform and Cell-Based Platform for Ocular Therapeutic Development

R.P 2.3 Developing Next-Generation Therapeutic Agents for Glaucoma

R.P 2.4 Novel Gene Delivery Platforms for the Treatment of Ocular Disease

R.P 2.5 Integrated Dry Eye Diagnosis and Precision Therapies

R.P 2.6 Development of Ocular Inserts and Aptamer-Based Delivery Vehicles for Sustained Release of Ocular Therapeutics and TCM Products

R.P 3.1 Eye Disease Diagnosis and Treatment Enabled by Novel Retinal Instrumentation

R.P 3.2 Non-Invasive Tear-Based Diagnostic System

R.P 3.3 Development of New-Generation Contact Lenses Using Novel Materials and Additive Manufacturing

R.P 3.4 Detection of Macular Degeneration and Myopia-Induced Retinal Damage Using Structured Light Technology

R.P 3.5 Extended Reality Visual Intelligence System (XRVIS) for Tele-Visual Assessment and Safety Enhancement for People with Visual Impairment

ENQUIRY